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PoE 2 Blasphemy Guide: Automate Your Curses and Dominate the Battlefield

In Path of Exile 2, keeping up with the fast-paced combat can be challenging, especially when juggling multiple skills, auras, and curses. That’s where the Blasphemy Meta Gem comes in. This powerful gem transforms your curses into auras, letting you automatically debuff enemies within a certain radius. No more stopping mid-fight to cast curses—Blasphemy streamlines your gameplay, giving you the edge you need to dominate the battlefield.
If you’re wondering how Blasphemy works, which curses to use, or how to fit it into your build, this guide has you covered. Let’s dive into everything you need to know about using Blasphemy in Path of Exile 2.

What is Blasphemy in Path of Exile 2?

Blasphemy is a Meta Gem in Path of Exile 2 that changes the way curses work. Normally, you have to cast curses manually, targeting specific enemies or areas. With Blasphemy, you can socket your curse gems into it, and they’ll automatically apply as auras to any enemies within range.
This means you can focus on dealing damage or staying mobile, while your curses do their work in the background. It’s a fantastic way to streamline your combat flow, especially in dense maps or fast-paced encounters.
blasphemy poe 2

How Does Blasphemy Work?

When you socket a curse into the Blasphemy Meta Gem, it converts that curse into an aura. This aura automatically affects all enemies within a certain radius, continuously applying the curse effect without you having to lift a finger.
Here’s a quick breakdown of how it functions:

  • Aura Conversion: Socketed curses become auras, automatically affecting nearby enemies.
  • Spirit Reservation: Each curse aura reserves 60 Spirit, which means you need to manage your Spirit pool carefully.
  • Reduced Effect: The curses you socket into Blasphemy have 41–50% reduced effect compared to manually cast curses. While this might sound like a drawback, the trade-off is worth it for the convenience and constant uptime.
  • Increased Radius: Blasphemy adds +1 meter to the radius of your curse auras, giving you a bit more coverage on the battlefield.

How to Obtain Blasphemy in Path of Exile 2

If you’re looking to get your hands on the Blasphemy Meta Gem, here’s how you can do it:

  1. Uncut Spirit Gem: You’ll need an Uncut Spirit Gem of level 8 or higher.
  2. Engraving: Take your Uncut Spirit Gem to the Gemcutting Menu and engrave it to unlock Blasphemy.

Once you’ve got the Blasphemy Meta Gem, you’re ready to start automating your curses and optimizing your build.

Best Curses to Use with Blasphemy

Not all curses are created equal when it comes to Blasphemy. Since the curse effect is reduced by up to 50%, you’ll want to choose curses that still pack a punch even with the diminished potency.
Here are some of the best curses to pair with Blasphemy:

  • Enfeeble — Great for defense-oriented builds. It reduces the damage output of enemies, making it easier to survive in tough encounters.
  • Temporal Chains — Slows down enemies, giving you more time to react. Even with a reduced effect, the slowing power is noticeable and can help control the battlefield.
  • Elemental Weakness — Perfect for elemental builds. This curse lowers the elemental resistances of enemies, boosting your elemental damage output.
  • Flammability / Frostbite / Conductivity — These curses target specific elemental resistances (fire, cold, lightning). Use them based on your build’s primary damage type.
  • Despair — If you’re running a chaos-damage build, Despair is your go-to curse. It reduces chaos resistance, amplifying your damage.

blasphemy poe2
Best Builds and Classes for Blasphemy

Blasphemy isn’t just for one type of player—it’s versatile enough to fit into a variety of builds. Here’s a look at some of the best classes and builds that benefit from Blasphemy in Path of Exile 2:

  • Witch (Blood Mage/Infernalist)
    Witches love curses, and Blasphemy makes it easier to keep those curses active. Blood Mage Witches can combine Blasphemy with life-based spellcasting for a powerful hybrid setup.

  • Mercenary (Witchhunter)
    Mercenaries who focus on hybrid ranged builds can use Blasphemy to weaken enemies while focusing on high-speed attacks.

  • Monk (Invoker)
    Monks who need to control the battlefield can use Blasphemy to apply defensive curses like Enfeeble or Temporal Chains while staying in the thick of melee combat.

  • Elemental Builds
    Any build that relies heavily on elemental damage can benefit from curses like Elemental Weakness, Flammability, or Conductivity.

  • Chaos-Damage Builds
    Chaos-focused builds, especially those using skills like Essence Drain or Contagion, will find Despair incredibly useful when paired with Blasphemy.

Pros and Cons of Using Blasphemy

Like any skill or gem in Path of Exile 2, Blasphemy has its upsides and downsides. Here’s what to consider before integrating it into your build:

Pros:

  • Automated Curse Application: No more manually casting curses—they’re always active.
  • Improved Efficiency: Frees up time to focus on damage output and movement.
  • Versatile for Many Builds: Works well with defensive, offensive, and hybrid setups.
  • Increased Radius: Covers more ground with +1 meter to curse radius.

Cons:

  • Reduced Effectiveness: Curses are 41–50% less effective than manually cast ones.
  • High Spirit Reservation: Each curse reserves 60 Spirit, limiting how many auras you can run.
  • Less Effective for Single-Target Bosses: In boss fights, manually casting curses might still be more effective.

Tips for Optimizing Blasphemy in Your Build

To get the most out of Blasphemy, you’ll need to manage your Spirit and choose the right curses for your build. Here are a few tips to help you optimize your setup:

  1. Manage Spirit Carefully: With each curse reserving 60 Spirit, be mindful of how many auras you’re running alongside Blasphemy. Prioritize the most impactful auras.
  2. Combine with Other Auras: Blasphemy can be paired with other defensive or offensive auras, but be cautious of Spirit limitations.
  3. Gear for Spirit Reservation Efficiency: Look for gear or passive skills that reduce Spirit reservation costs to free up more space for other skills.
  4. Balance Curse Selection: Choose curses that align with your build’s strengths. If you’re running an elemental build, prioritize curses that reduce elemental resistances.

Where to Trade for Blasphemy and Currency Tips

If you’re not keen on farming for the Uncut Spirit Gem needed to unlock Blasphemy, you can always trade for it in the marketplace. To speed up the process, consider using SSEGold for your Path of Exile 2 currency needs. With quick and reliable service, SSEGold can help you get the currency you need to purchase Blasphemy and other high-end gear without spending hours grinding.

Conclusion: Is Blasphemy Worth It?

If you’re looking to simplify your gameplay and keep your curses active at all times, Blasphemy is an invaluable Meta Gem in Path of Exile 2. Whether you’re running a tanky Witch, a fast-hitting Mercenary, or a chaos-focused caster, Blasphemy lets you automate one of the most important aspects of your build. Just keep an eye on your Spirit reservation and choose your curses wisely, and you’ll find that Blasphemy can take your build to the next level.
Happy hunting!

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